Selected Publications

Immunotherapy & Inflammasome Research

Alphonse MP, Rubens JH, Ortines RV, Orlando NA, Patel AM, Dikeman DA, Wang Y, Vuong I, Joyce DP, Zhang J, Mumtaz M, Liu H, Liu Q, Yuon C, Patrick GJ, Ravipati A, Miller RJ, Archer NK, Miller LS. Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections. Science Translational Medicine. 2021 Jul 7;13(601):eabe9887. PMID: 34233954

Skin Microbiome & Allergic Disease

Patrick GJ*, Liu H*, Alphonse MP, Dikeman DA, Youn C, Otterson JC, Wang Y, Ravipati A, Mazhar M, Denny G, Ortines RV, Zhang E, Miller RJ, Dillen CA, Liu Q, Nolan SJ, Nguyen K, Marcello L, Do DC, Zhang Y, Caviness G, Klimowicz AC, Mierz DV, Fine JS, Sun G, Goldbach-Mansky R, Marusina AI, Merleev AA, Maverakis E, Milner JD, Gao P, Ramanujam M, Raymond EL, Archer NK*, Miller LS*. Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease. Journal of Clinical Investigation. 2021;131(5):e143334. PMID: 33645549 * – Equal contribution

Prurigo Nodularis Research

Alphonse MP*, Belzberg M*, Brown I, Williams KA, Khanna R, Ho B, Wongvibulsin S, Pritchard T, Jedrych J, Johnston A, Sarkar K, Vasavda C, Meixiong J, Dillen CA, Chen W, Corcoran D, Devos N, Kwatra MM, Chien AL, Archer NK, Garza LA, Dong X, Kang S, Kwatra SG. Prurigo nodularis is characterized by systemic and cutaneous Th22 immune polarization. Journal of Investigative Dermatology. 2021 Sep;141(9):2208-2218.e14. PMID: 33771530 *– Equal contribution – Co-first author

Alphonse MP*, Sutaria N*, Roh YS, Choi J, Parthasarathy V, Deng J, Bordeaux ZA, Taylor MT, Pritchard T, Kim N, Aguh C, Semenov YR, Archer NK, Garza LA, Kang S, Kwatra SG. Cutaneous transcriptomics identifies fibroproliferative and neurovascular gene dysregulation in prurigo nodularis compared to psoriasis. Journal of Investigative Dermatology. 2022 Mar 4:S0022-202X(22)00175-0. PMID: 35257721 *– Equal contribution – Co-first author

Skin Regeneration

Wang G, Liu H, Sweren E, Wier E, Alphonse MP, Islam N, Li A, Xue Y, Wang SLY, Archer NK, Hu Z, Grice E, Miller LS, Garza LA. Bacteria Induce Skin Regeneration via IL-1β Signaling. Cell Host & Microbe. 2021 May 12;29:1-15. PMID: 33798492MP.